1-METHYL-1H-INDOLE-3-CARBOXYLIC ACID

1-METHYL-1H-INDOLE-3-CARBOXYLIC ACID - Names and Identifiers

Name	1-methylindole-3-carboxylic acid
Synonyms	Ramosetron Impurity 7 N-Methylindole acetate Methylindole-3-carboxylic 1-METHYL-3-INDOLECARBOXYLIC ACID 1-methylindole-3-carboxylic acid 1-METHYLINDOLE-3-CARBOXYLIC ACID 1-METHYL-1H-INDOLE-3-CARBOXYLIC ACID 1-methyl-1H-indole-3-carboxylic acid 1H-Indole-3-carboxylic acid, 1-Methyl-
CAS	32387-21-6
InChI	InChI=1/C10H9NO2/c1-11-6-8(10(12)13)7-4-2-3-5-9(7)11/h2-6H,1H3,(H,12,13)

1-METHYL-1H-INDOLE-3-CARBOXYLIC ACID - Physico-chemical Properties

Molecular Formula	C10H9NO2
Molar Mass	175.18
Density	1.24±0.1 g/cm3(Predicted)
Melting Point	197-200 °C (dec.) (lit.)
Boling Point	389.0±15.0 °C(Predicted)
Flash Point	189°C
Vapor Presure	9.54E-07mmHg at 25°C
Appearance	Crystalline Powder
Color	White to beige
pKa	4.01±0.10(Predicted)
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.612
MDL	MFCD01321244

1-METHYL-1H-INDOLE-3-CARBOXYLIC ACID - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
HS Code	29339900
Hazard Class	IRRITANT

1-METHYL-1H-INDOLE-3-CARBOXYLIC ACID - Introduction

acid is an organic compound with a chemical formula of C10H9NO2 and a molecular weight of 175.18g/mol. The following is a detailed introduction to the nature, use, preparation and safety information of acid:

Nature:
acid is a white crystalline solid, soluble in some polar solvents such as alcohols and ketones, insoluble in water. It is relatively stable to air and moisture.

Use:
as an important intermediate for organic synthesis, acid is widely used in the synthesis of other indole compounds. Indole compounds have important application value in drug synthesis and pesticide research and development.

Method:
There are many methods for preparing acid, and a common method is obtained by the reaction of 1-methylindole and chloroformic acid. The specific reaction conditions can be adjusted according to the experimental needs.

Safety Information:
The acid has less impact on the human body and the environment under general operating conditions, but it is still necessary to pay attention to safe operation. Wear appropriate personal protective equipment during use to ensure good ventilation and avoid inhalation, ingestion and contact with skin and eyes. When storing and handling the compound, the relevant safety practices should be observed to avoid contact with oxidizing agents and flammable substances. In case of accidental leakage, corresponding emergency treatment measures shall be taken in time.

Last Update：2024-04-09 02:00:45